Study predicts that routine immunization with the first typhoid conjugate vaccine could avert 46-74% of typhoid fever

Researchers from Yale University, University of Basel, University of Antwerp, CDDEP and other institutions recently published 'Estimating the effect of vaccination on antimicrobial resistant typhoid fever in 73 countries supported by Gavi: a mathematical modelling study' in The Lancet Infectious Diseases. The study aimed to assess how vaccination against typhoid fever could help avert antimicrobial resistance both directly, by preventing transmission of resistant infections, and indirectly, by preventing cases of infection caused by antimicrobial susceptible S Typhi that would otherwise be treated with antibiotics and develop resistance.