Team develops new mouse model to shed light on the mystery surrounding Huntington's disease onset

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models. It is providing new clues to the mystery surrounding how genetic mutations dictate disease onset and giving researchers a powerful new tool to test new therapies engaging multiple targets to treat the devastating neurological disorder.